The GISAID Initiative benefits from substantial in-kind contributions from technical partners and commercial service providers with the common goal of strengthening the Initiative's important role in global health
The Bioinformatics Institute (a member of Singapore's A*STAR's Research Entities) provides the CoVsurver and FluSurver power the analysis of data in GISAID to highlight mutations relative to reference strains, display them in the 3D protein structure, cross-link with prior literature phenotype information (antiviral susceptibility, host specificity, glycosylation and antigenic properties), view their geographic and temporal frequency of occurrence as well as co-occurrence with other mutations.
Institut Pasteur's Department of Computational Biology and its Bioinformatics and Biostatistics HUB powers GISAID's automated curation pipeline for hCoV-19 data and provides advanced tools for its analysis including COVID-Align, for accurate online alignment of genomes using a profile HMM, or NGPhylogeny to aid in the reconstruction and analysis of phylogenetic relationships between molecular sequences. To infer ancestral characters on a rooted phylogenetic tree with annotated tips, PastML uses maximum likelihood or parsimony with the results visualized as a zoomable html map.
The GISAID homepage was designed in collaboration with the creative team of Silke Arend at a7digital GmbH using the flexibility of open source CMS technology TYPO3 as a basis to permit the access of a wide range of content contributors commensurate with the needs of GISAID's global participation.